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Updated: Sep 11, 2025

Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo
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Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo

Published on: September 18, 2014

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具有NIR开关的DNA快门可实现可逆间歇cGAS-STING激活,增强抗瘤免疫力

Shiyi Bi1, Ruowen Yang1, Yulin Cong1

  • 1State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.

Journal of the American Chemical Society
|August 18, 2025
PubMed
概括

这项研究引入了间歇性STING激动剂用于免疫治疗. 这种新的方法使用可逆激活来增强免疫反应和瘤细胞杀死,克服与持续途径刺激相关的抵抗.

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