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Updated: Sep 11, 2025

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患有COVID-19的90天以上的发烧婴儿存在严重细菌感染风险
Rufu Furuya1, Shun Kishibe2, Takahiro Itagaki3
1Department of General Pediatrics, Tokyo Metropolitan Children's Medical Center, Tokyo, JPN.
Cureus
|August 18, 2025
概括
患有COVID-19的90天以下发烧的婴儿与没有病毒的婴儿相比,严重细菌感染 (SBI) 的风险明显较低. 然而,尿路感染 (UTI) 仍然是一个问题,需要进行尿液分析.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 在COVID-19发烧的婴儿中,严重细菌感染 (SBI) 的风险尚未完全理解,特别是在日本.
- 以前的研究表明,COVID-19阳性婴儿的SBI风险可能较低.
研究的目的:
- 为了比较患有SBI的发病率和临床特征,在患有COVID-19的和没有COVID-19的90天以上发烧的婴儿中进行SBI的发生率和临床特征.
- 调查COVID-19诊断的婴儿中特定类型的SBI.
主要方法:
- 对发烧婴儿 (≤90天) 访问日本儿童医院 (2021年4月至2022年11月) 的回顾性队列研究.
- 通过阳性PCR或密切接触定义的COVID-19组;非COVID-19组作为对照.
- 其中SBI包括尿路感染 (UTI),细菌性肺炎,细菌病和脑膜炎.
主要成果:
- 包括396名婴儿;125人在COVID-19组.
- 在COVID-19组中,SBI发生率为5.6%,而非COVID-19组为16.6% (p<0.05).
- 在COVID-19组中的所有SBI都是尿路感染;在呼吸道/胃肠道症状中没有显著差异.
结论:
- 在COVID-19阳性发烧婴儿中,SBI的发生率明显较低.
- SBI,特别是尿路感染的风险不是可以忽视的,支持发烧的婴儿的尿液分析.
- 这些发现为了解COVID-19发烧婴儿SBI风险的理解增加了证据.
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