血液中的行为菌:病原体还是乘客?
Zaraq R Khan1, Lama Hanbali2, Imad Majeed1
1Infectious Diseases, University of Louisville Hospital, Louisville, USA.
Cureus
|August 18, 2025
概括
Actinomyces bacteremia通常在临床上无关紧要,大多数患者不需要治疗. 这项研究表明,在血液培养中对Actinomyces的抗生素治疗采取谨慎的方法.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 临床诊断 临床诊断 临床诊断
背景情况:
- Actinomyces物种是常见的口腔和胃肠菌群.
- 分子识别的进步使血液培养中的Actinomyces的解释变得复杂.
- 关于Actinomyces bacteremia的临床意义的数据有限.
研究的目的:
- 为了评估Actinomyces bacteremia的临床相关性.
- 评估Actinomyces bacteremia对治疗决策的影响.
- 为了告知对Actinomyces bacteremia的明智抗生素使用.
主要方法:
- 对18名患有Actinomyces bacteremia的患者进行了回顾性,横截面研究.
- 数据收集于2022年6月至2023年5月的路易斯维尔大学医疗保健.
- 图表审查包括临床表现,治疗,成像和结果.
主要成果:
- 大多数患者 (88.89%) 没有接受Actinomyces bacteremia的治疗.
- 平均随访时间为6.58个月.
- 死亡率为33.33%,有些死亡与Actinomyces无关.
结论:
- 这种细菌病常常在临床上无关紧要.
- 在大多数情况下,可能不需要长时间的抗生素治疗.
- 建议对治疗采取谨慎的方法.
相关概念视频
Bacterial Phylum Actinobacteria
112
Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...
112
Fungal Phylum Microsporidia
117
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
117
Intracellular Movement of Viruses and Bacteria
2.9K
Intracellular bacteria and viruses often comprise a group of highly infectious pathogens that can cause several diseases. Bacterial pathogens include those belonging to the genus Rickettsia responsible for conditions such as rocky mountain spotted fever and the Mediterranean spotted fever; Chlamydia, a genus responsible for a sexually transmitted disease; Coxiella burnetii, an agent responsible for Q fever. Viral pathogens include vaccinia—a poxvirus, and herpes simplex virus—a...
2.9K
Bacterial Phylum Spirochaetes
114
Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
114
Bacterial Phylum Chlamydiae
109
The phylum Chlamydiae or Chlamydiota is composed of a single order, Chlamydiales. This phylum consists entirely of obligate intracellular parasites that infect eukaryotic hosts. While human pathogens within this group have been studied extensively, the phylum encompasses many species capable of interacting with various eukaryotic organisms. Members of Chlamydiae are typically small cocci, approximately 0.5 μm in diameter, and exhibit a distinctive developmental cycle. As is characteristic...
109
Infection
8.7K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
8.7K


