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相关概念视频

Accessory Structures of the Skin: Nails01:05

Accessory Structures of the Skin: Nails

2.0K
Nails are one of the important accessory structures of the skin. They are hard, protective structures that cover the dorsal surface of the distal phalanges of fingers and toes. Nails are composed of specialized keratinized cells and serve various functions, including protection, sensation, and manual dexterity.
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
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Vitamins01:30

Vitamins

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Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
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Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
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Skin Diseases and Disorders01:23

Skin Diseases and Disorders

4.1K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

6.5K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
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Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
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相关实验视频

Updated: Sep 11, 2025

Author Spotlight: Unraveling Vitamin A Transport Mechanisms — Linking Liver Receptors to Vision Health Through RBPR2 and RBP4 Interactions
08:18

Author Spotlight: Unraveling Vitamin A Transport Mechanisms — Linking Liver Receptors to Vision Health Through RBPR2 and RBP4 Interactions

Published on: October 4, 2024

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维生素A相关的阴溶解.

Sloan Long1, Peyton Harris1, Ronnie Youssef2

  • 1Texas A&M School of Medicine, Dallas, Texas, USA.

Proceedings (Baylor University. Medical Center)
|August 18, 2025
PubMed
概括

解或指甲分离可能是高剂量维生素A治疗的未报告的副作用. 这项案例研究表明,长时间摄入维生素A与指甲变化之间存在联系.

科学领域:

  • 皮肤病学 皮肤病学
  • 毒理学 毒理学 毒理学
  • 营养科学 营养科学

背景情况:

  • 甲状腺溶解是指甲板与指甲床的分离,通常是由创伤或光敏感引起的.
  • 像视网类药物这样的药物,合成维生素A衍生物,与指甲变化有关.
  • 之前没有任何报告将口服维生素A摄入与乳溶解联系起来.

研究的目的:

  • 报告可能由维生素A疗法引起的乳溶解病例.
  • 调查维生素A补充剂与指甲疾病之间的关联.

主要方法:

  • 一个85岁的老妇人患有远端阴茎溶解的病例报告.
  • 审查患者的药物历史,包括处方和非处方维生素A.
  • 维生素A停止后症状消失的观察.

主要成果:

  • 患者经历了5天高剂量维生素A疗程和随后2个月的非处方补充剂后,经历了远端肌肉溶解.
  • 在停止服用维生素A后,症状有所改善.
  • 这表明,维生素A和乳溶解之间可能存在联系.

结论:

  • 耳溶解可能是维生素A治疗的未报告的副作用.
关键词:
药物诱导的光氧化溶解这是一种异氨酸 (isotretinoin).指甲缩症指甲缩症指甲缩症指甲缩症基溶解是一种基溶解.维生素A是一种维生素A.

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Author Spotlight: Investigating Physiological Functions of Vitamin A Transporters Using HPLC-Based Vitamin A Profiling
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Author Spotlight: Unraveling the Pathogenesis of Age-Related Macular Degeneration and Discovering Potential Therapies
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Last Updated: Sep 11, 2025

Author Spotlight: Unraveling Vitamin A Transport Mechanisms — Linking Liver Receptors to Vision Health Through RBPR2 and RBP4 Interactions
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Author Spotlight: Investigating Physiological Functions of Vitamin A Transporters Using HPLC-Based Vitamin A Profiling
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Author Spotlight: Investigating Physiological Functions of Vitamin A Transporters Using HPLC-Based Vitamin A Profiling

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Author Spotlight: Unraveling the Pathogenesis of Age-Related Macular Degeneration and Discovering Potential Therapies
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  • 需要进一步的研究来证实维生素A和乳溶解之间的关联.
  • 临床医生应考虑维生素A的摄入量,在评估患有乳溶解的患者时.