工作日睡眠时间和COPD风险之间的非线性关联:来自NHANES的证据 2017-2023
Xinxin Tao1, Xianwei Ye1,2
1School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou, People's Republic of China.
International journal of chronic obstructive pulmonary disease
|August 18, 2025
概括
较长的周日睡眠时间 (WSD) 与患慢性阻塞性肺部疾病 (COPD) 的风险更高有关. 这一发现表明WSD可能是COPD预防策略的一个因素.
科学领域:
- 肺部医学 肺部医学
- 流行病学 流行病学
- 睡眠科学 睡眠科学
背景情况:
- 慢性阻塞性肺病 (COPD) 是一个重大的全球健康挑战.
- 生活方式因素对于预防COPD至关重要.
- 这项研究调查了周日睡眠时间 (WSD) 与美国人口中COPD患病率之间的联系.
研究的目的:
- 探索周日睡眠时间 (WSD) 与慢性阻塞性肺部疾病 (COPD) 的患病率之间的潜在联系.
- 为了确定与COPD风险增加相关的睡眠持续时间模式.
主要方法:
- 利用了2017-2023年国家健康和营养检查调查 (NHANES) 的数据.
- 采用加权后勤回归,对通过定向环形图 (DAG) 识别的共变量进行调整.
- 应用了LASSO回归,灵敏度分析,限制立方 (RCS) 和子组分析来验证发现.
主要成果:
- 较高的WSD显示出与COPD患病率增加的一致相关性 (OR=1.740,P=0.012).
- RCS和值分析显示,COPD和WSD之间的正相关性在7.0-14.0小时之间 (OR=1.12,P=0.011).
- 亚组分析表明,WSD和COPD之间存在显著的积极关联,特别是周末赶上睡眠 (P=0.000).
结论:
- 每天8.5-14小时的周日睡眠时间与COPD风险增加有关.
- 这种新的见解需要通过对COPD预防和治疗策略的前性研究进行进一步的调查.
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