腰椎间盘的患者的结果测量 - - 范围审查
N Gabrovsky1, M Petrov1, Y Kotceva1
1Department of Neurosurgery, University Multiprofile Hospital for Active Treatment with Emergency Medicine "N. I. Pirogov", Sofia, Bulgaria.
Brain & spine
|August 18, 2025
概括
这次审查确定了29种用于168项腰椎间盘 (LDH) 随机对照试验的结果测量工具. 疼痛,残疾和生活质量通常被评估,新的数字工具正在出现.
科学领域:
- 整形外科和康复治疗
- 临床试验方法论 临床试验方法论
- 健康 结果 研究 研究 结果
背景情况:
- 结果测量在现代医学中至关重要,特别是在评估腰椎间盘 (LDH) 的治疗方法时.
- 在临床实践和LDH研究中使用各种结果测量工具 (OMT).
- 标准化和验证的OMT对于可靠的治疗疗效评估至关重要.
研究的目的:
- 识别和分类过去25年来用于腰椎间盘 (LDH) 随机对照试验 (RCT) 的结果测量工具 (OMT).
- 在LDH RCT中分析OMT应用的领域和频率.
- 提供当前OMT的概述,并突出LDH结果评估中的新兴趋势.
主要方法:
- 对从2000年1月1日到2024年12月31日期间涉及LDH成年患者的RCT进行了全面的文献搜索.
- 两个独立的审查者选了RCT与LDH结果测量的相关性.
- 关于OMT的数据被提取,标准化,并在不同的领域进行分类.
主要成果:
- 总共有168个RCT被确定,使用29个不同的结果测量工具.
- 这些工具涵盖了六个主要领域:疼痛 (6 个工具),残疾 (4 个工具),生活质量 (2 个工具),临床参数 (9 个工具),心理因素 (3 个工具) 和自我感知恢复 (5 个工具).
- 大多数RCT (26.2%) 使用3个OMT,而21.4%使用4个OMT. 常用的工具包括用于疼痛的VAS,用于残疾的ODI和用于生活质量的SF-36/12.
结论:
- 评估腰椎间盘 (LDH) 的结果是一个复杂的,多维的过程.
- 对于手术LDH治疗的RCT通常测量疼痛,残疾,临床参数和生活质量.
- 新兴的数字成果指标和可穿戴设备显示出希望,但需要进一步调查标准化和验证.
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