通过跨膜光生物调节改善睡眠,清醒和认知:一个系统性审查
Naomi L Gaggi1, Zamfira Parincu1, Anna Peterson1
1Grossman School of Medicine, New York University, New York, NY, United States.
Frontiers in behavioral neuroscience
|August 18, 2025
概括
跨膜光生物调制 (t-PBM) 通过提高大脑能量和血液流动,可以增强睡眠和清醒. 这篇评论探讨了t-PBM.
科学领域:
- 神经科学是一个神经科学.
- 睡眠科学 睡眠科学
- 照相医疗 (photomedicine) 是一种医学.
背景情况:
- 睡眠障碍在神经和精神疾病中普遍存在,影响公众健康.
- 充足的睡眠对认知功能,记忆巩固和健康的衰老至关重要.
- 正在探索神经调节技术以解决睡眠和清醒缺陷的问题.
研究的目的:
- 系统地审查关于改善睡眠,清醒和认知的跨膜光生物调节 (t-PBM) 的文献.
- 检查t-PBM对大脑线粒体活动,血液流动和淋巴系统的影响.
- 建议未来的研究方向,针对临床人群中针对性的t-PBM应用.
主要方法:
- 对调查t-PBM对睡眠,清醒和认知的影响的研究进行系统文献综述.
- 神经生物学机制的分析,包括对线粒体功能和脑血流的影响.
- 包括来自临床和健康人群的数据.
主要成果:
- t-PBM显示了改善睡眠质量和持续清醒的潜力.
- 观察到的效应与大脑线粒体活动增加和血液流量增加有关.
- t-PBM可能会积极影响与警觉和清醒相关的认知过程.
结论:
- 跨膜光生物调制 (t-PBM) 显示出作为治疗睡眠和清醒障碍的治疗策略的希望.
- 需要进一步的研究来阐明t-PBM的神经生物学机制并优化其应用.
- 有针对性的t-PBM干预可以使各种临床人群受益,这些人群经历了睡眠和认知障碍.
相关概念视频
Brain Imaging
312
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
312
Management of Insomnia
320
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
320
Understanding Sleep
503
Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
503


