预期的中风两年后,心房 Septal 缺陷关闭: 晚期器件栓塞的一个案例
Nuria Pueyo-Balsells1, Ignacio Barriuso2, Marta Zielonka1
1Department of Cardiology Arnau de Vilanova University Hospital Lleida Spain.
Clinical case reports
|August 18, 2025
概括
一名患有甲基基酸缩酶基因突变的患者在心房隔膜缺陷关闭后因器件栓塞而患上中风. 长期监测和成像对于管理这种血栓友爱并发症至关重要.
科学领域:
- 心血管医学 心血管医学
- 遗传学 是一个遗传学.
- 神经学 神经学
背景情况:
- 耳前隔膜缺陷 (ASD-OS) 有时可以使用跨导管装置来关闭.
- 遗传性血栓塞,如MTHFR C677T突变,可以增加栓塞事件的风险.
- 器件栓塞是一种罕见但严重的过导管手术并发症.
研究的目的:
- 在患有血栓友爱症的患者中,报告跨导管ASD关闭后晚期器件栓塞的病例.
- 强调长期监测和多式联络成像在管理设备相关并发症方面的重要性.
主要方法:
- 使用Figulla Flex II装置,通过导管关闭骨第二心房隔膜缺陷 (ASD-OS).
- 诊断成像 (如CT,MRI) 以确定设备迁移和评估栓塞事件.
- 临床评估和无症状器械栓塞的保守管理.
主要成果:
- 一名42岁的女性患有MTHFR C677T突变和先前的过渡性缺血性发作,经历了成功的ASD-OS关闭.
- 术后两年,她经历了一次缺血性中风,原因是关闭装置到大动脉-阴茎分叉的晚期栓塞.
- 患者从栓塞装置中保持无症状,并成功地进行了第二次跨导管ASD-OS闭合.
结论:
- 遗传性血栓性可能会导致复发的栓塞事件,即使在成功关闭缺陷后.
- 长期监测至关重要,以检测透导管关闭装置的晚期并发症.
- 多式成像在指导临床决策中发挥着至关重要的作用,用于与设备相关的问题和栓塞事件.
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