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Updated: Sep 11, 2025

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling
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基于双因素神经再生生物活性涂层支架的神经活性网络组织和神经干细胞用于脊髓损伤修复

Tianyi Liu1, Wenhao Zhu2, Zheng Wan1

  • 1Department of Neurosurgery, The First Hospital of Jilin University, Changchun, 130021, China.

Materials today. Bio
|August 18, 2025
PubMed
概括

这项研究介绍了一种新的神经活性网络组织,它使用双重生长因子和神经干细胞来修复脊髓损伤 (SCI). 该治疗促进神经再生,并重塑免疫环境,以增强组织修复.

关键词:
固定化的复合生长因子神经干细胞对神经干细胞的影响神经活性网络组织组织的神经活性网络组织.单细胞 rnaseq 分析脊髓损伤导致的脊髓损伤

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Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration08:52

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Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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