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怀孕期间对B组菌株的查:对实验室检测的系统审查
Valentina Arsić Arsenijević1, Vladimir Gerginić2, Biljana Miličić3
1Institute of Microbiology and Immunology, Medical Mycology Reference Laboratory (MMRL), University of Belgrade Faculty of Medicine, Dr Subotića 1, Belgrade, 11000, Serbia.
Open medicine (Warsaw, Poland)
|August 18, 2025
概括
针对B组链球菌 (GBS) 的全方位产前查对于预防新生儿感染至关重要. 目前的测试方法显示出显著的变化,需要负担得起,高灵敏度的测试广泛使用.
科学领域:
- 微生物学 微生物学
- 产科 产科 产科 产科 产科
- 新生儿护理 新生儿护理
背景情况:
- 乙组链球菌 (GBS) 殖民影响了近三分之一的孕妇.
- 将GBS传播给新生儿可能会导致严重的早期感染.
- 目前的指导方针要求对GBS进行产前查,但其他病原体也会带来风险.
研究的目的:
- 系统地审查有关GBS产前查的现行做法和证据.
- 确定GBS检测和预防新生儿感染的最佳方法.
主要方法:
- 使用Web of Science,Scopus和PubMed进行了系统的文献审查.
- 该审查分析了20项研究,重点关注GBS流行,测试方法,样本类型和时间.
主要成果:
- 在10,288名患者中观察到13%的GBS患病率.
- 根据测试方法,患病率有显著差异 (常规的0.2-20.8%,分子的37-45%).
- 只有三项研究使用了推的阴道/直肠拭子方法.
结论:
- 在GBS检测和识别中的异质性限制了临床实用性.
- 需要使用负担得起的,高灵敏度的传统测试进行普遍的产前查.
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