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与皮质类固醇眼滴相关的阳性上腺功能不全:一个病例报告
Shruthi Rayen1, Manjusha Rathi1
1Endocrinology Department, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK.
JRSM open
|August 18, 2025
概括
长期的眼内皮质类固醇使用可能导致上腺功能不全. 患者和医生应讨论风险,并考虑对这种情况进行监测.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
背景情况:
- 眼内皮质类固醇经常用于各种眼部疾病.
- 长时间使用皮质类固醇,不管是通过哪种方式服用,都会带来潜在的全身副作用.
研究的目的:
- 要突出与长期眼内皮质类固醇治疗相关的上腺功能衰竭风险.
- 强调患者和临床医生的意识对这种潜在的不良影响的重要性.
主要方法:
- 这是关于眼内皮质类固醇使用现有知识和临床观察的总结.
- 没有采用特定的实验方法;它依赖于临床数据和文献审查.
主要成果:
- 长期服用眼内皮质类固醇可以抑制下丘脑-垂体-上腺 (HPA) 轴.
- 这种抑制会导致上腺功能不充分,这是一种上腺不能产生足够的类固醇激素的情况.
结论:
- 接受长期眼内皮质类固醇治疗的患者有患上上腺功能衰竭的风险.
- 接受知情同意和定期监测HPA轴抑制对于长期眼内类固醇治疗的患者的管理至关重要.
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