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Updated: Sep 11, 2025

Monitoring eIF4F Assembly by Measuring eIF4E-eIF4G Interaction in Live Cells
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核心转录调节电路调节的IGF2BP3通过m6A修改稳定了神经母细胞瘤中的E2F2mRNA

Pengcheng Yang1,2, Jianwei Wang1, Ziheng Wu1,3

  • 1Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215003, China.

Carcinogenesis
|August 18, 2025
PubMed
概括

神经母细胞瘤的进展是由IGF2BP3-E2F2轴驱动的,这涉及N6-甲基氨酸 (m6A) 修饰. 针对这种途径为儿童癌症提供了潜在的治疗策略.

关键词:
核心转录性调节电路 (CRC)N6 - 甲基氨酸 (m6A) 的使用.神经母细胞瘤是一种神经母细胞瘤.m6A阅读器的使用在mRNA的稳定性上.

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