含有磁性玻璃陶颗粒的Palacos® MV骨的机械性能
Fatma Ozdemir1, Iain Evans1, Oana Bretcanu1
1School of Engineering, Newcastle University, Newcastle upon Tyne, UK.
概括
新的磁性聚甲基甲酸盐 (PMMA) 骨显示了治疗骨癌的潜力. 这些水泥,结合磁性玻璃陶,满足关键的机械标准,用于骨科应用,特别是高达30%的重量%的磁性含量.
科学领域:
- 生物材料科学 生物材料科学
- 整形外科手术 整形外科手术
- 材料工程 材料工程 材料工程
背景情况:
- 聚甲基甲酸 (PMMA) 是骨科治疗中广泛使用的骨质水泥,用于假肢固定和骨缺陷修复.
- 磁性PMMA骨正在研究通过磁感应高温来治疗骨癌.
- 开发有效的磁性骨水泥需要仔细的配方,以平衡磁性和机械完整性.
研究的目的:
- 通过将磁性玻璃陶融入商业PMMA骨水泥中,开发和描述新的磁性骨水泥.
- 根据国际标准 (ISO 5833:2002和ASTM E384-22) 评估这些磁性骨的机械性能.
- 评估这些磁性骨水泥在骨癌治疗应用中的潜力.
主要方法:
- 磁性骨水泥的配方是通过将不同百分比 (高达40重量%) 的磁性玻璃陶与Palacos® MV PMMA骨水泥混合而创建的.
- 测试了包括设置时间,设置温度,压力强度,曲强度和曲模量在内的机械性能.
- 维克尔硬度被测量以评估材料表面的性能.
主要成果:
- 设置时间随着磁性玻璃陶含量增加而增加.
- 磁性和非磁性水泥的设置温度是可比的.
- 所有测试的磁性骨水泥都符合压力强度 (>70 MPa) 和曲模量 (>1.8 GPa) 的要求.
- 具有高达30%重量%磁性玻璃陶的磁性骨水泥符合曲强度要求 (>50 MPa).
- 所有磁性骨都表现出比对照组更高的维克尔硬度.
结论:
- 磁性骨水泥含有高达30%的磁性玻璃陶,具有适合于骨科应用的机械性能.
- 这些配方在使用磁感应高温疗法治疗骨癌方面表现有前途.
- 需要进一步的研究,以优化磁性骨质水泥配方的临床转化.
相关概念视频
01:18Porosity in Cement Paste
223
The porosity of concrete is a measure of the void spaces within its structure. These spaces impact its strength and durability significantly. When water and cement interact, a chemical reaction called hydration creates a semi-solid paste. This paste includes combined water, making up approximately 23% of the cement's dry mass, and gel water, which fills minuscule voids known as gel pores, accounting for about 28% of the cement gel volume.
The balance of water to cement in the mix is...
The balance of water to cement in the mix is...
223
01:17Mortar Properties
187
Mortar properties encompass a range of characteristics crucial for construction and masonry work, including workability, water retention, bond strength, durability, compressive strength, volume change, and appearance. Workability refers to mortar's ability to be easily applied and manipulated without sagging or falling off surfaces, which is important for efficient masonry unit placement and alignment. Water retention is essential to prevent the mortar from losing moisture too quickly to...
187