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糖尿病分娩中的血糖控制:GILD,一个范围研究
Nia Wyn Jones1, Eleanor J Mitchell1,2, Kate F Walker1
1Centre for Perinatal Research, School of Medicine, University of Nottingham, Nottingham, UK.
一项新的研究设计了一项可行的临床试验,用于比较糖尿病孕妇在分娩期间的宽容和密集血糖控制. 这种方法对患者和医疗保健专业人员来说是可以接受的,为未来的研究铺平了道路.
科学领域:
- 产科和妇科 产科和妇科
- 内分泌学 在内分泌学.
- 临床试验设计 临床试验设计
背景情况:
- 孕期糖尿病影响5-10%的怀孕.
- 产后血糖控制不良与新生儿不良结果有关.
- 目前严格的血糖控制是繁重的,可能并不总是必要的.
研究的目的:
- 评估随机临床试验的可行性.
- 为了比较糖尿病怀孕的孕妇的容许性与密集性产后血糖控制.
- 为了评估临床和成本效益.
主要方法:
- 混合方法研究包括指导审计,调查和服务评估.
- 开发一个非劣势保护试验协议.
- 定性访谈,以评估试验的可接受性.
主要成果:
- 在目前的临床实践中,对于产后血糖管理存在显著的差异.
- 66%的受访女性表示愿意参加未来的试验.
- 开发了一个可行和可接受的雨试验设计.
结论:
- 将允许和强化血糖控制进行比较的综合试验是可行的和可接受的.
- 这种方法解决了在糖尿病怀孕中最佳产后葡萄糖管理的需要.
- 建议在内部试点阶段进行进一步的研究.
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