干预措施对印度上学儿童缺铁性贫血的影响:系统性审查和网络元分析
Flemin Felix1, Kalesh Mappilakudy Karun1, Chandan Nagendraswamy1
1Department of Health Systems Research, ICMR - National Institute of Traditional Medicine, Nehru Nagar, Belagavi, 590010, Karnataka, India.
Journal of research in health sciences
|August 18, 2025
概括
富含铁的鱼粉和间歇性铁和叶酸 (IFA) 补充剂在治疗印度学龄儿童的缺铁性贫血 (IDA) 方面表现有前途. 需要进一步的研究来证实这些发现及其对公共卫生的影响.
科学领域:
- 公共卫生 公共卫生
- 营养科学 营养科学
- 儿科 儿科 儿科
背景情况:
- 缺铁性贫血 (IDA) 在印度学龄儿童中非常普遍,患病率从27%到90%不等.
- 有限的证据表明,在这个人群中,各种IAD干预措施的比较有效性有限.
- 为了解决这一知识差距,进行了系统性审查和元分析.
研究的目的:
- 量化和排名不同干预措施对印度学龄儿童缺铁性贫血 (IDA) 的影响.
- 确定改善血红蛋白 (Hb) 和血清费里水平的最有效的干预措施.
主要方法:
- 进行了随机对照试验 (RCT) 的系统审查和元分析.
- 在PubMed,Scopus和ScienceDirect数据库中进行了搜索.
- 使用随机效应和固定效应模型分别分析了Hb和血清费里水平的数据.
主要成果:
- 八个涉及2534名参与者的RCT评估了IDA的12种不同的干预措施.
- 富含铁的鱼粉在提高Hb水平方面表现出最高的有效性 (MD:2.07g/dL).
- 每周两次间歇性铁和叶酸 (IFA) 补充剂在提高血清费里水平方面最有效 (MD:0.80 ng/mL).
结论:
- 富含铁的鱼粉和间歇性IFA补充似乎是IDA在学龄儿童中最有效的干预措施.
- 建议进行进一步的研究,以验证这些发现,并评估其更广泛的公共卫生影响.
- 协议注册:CRD42024541802.02 编号: 编号: 编号: 编号:
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