自主神经系统与控制呼吸过程中的大脑自我调节之间的关系
Agnieszka Uryga1, Monika Najdek2, Piotr Urbański3
1Department of Biomedical Engineering, Wroclaw University of Science and Technology, Wybrzeze Wyspianskiego 27, 50-370, Wroclaw, Poland. agnieszka.uryga@pwr.edu.pl.
European journal of applied physiology
|August 18, 2025
概括
控制呼吸会影响自主神经系统 (ANS) 活动和大脑自我调节. 较高的呼吸速率降低了心血管合和ANS功能,改变了ANS-大脑自我调节关系.
科学领域:
- 生理学 生理学 生理学
- 神经科学是一个神经科学.
- 心血管研究研究心血管研究
背景情况:
- 控制呼吸是一种已知的影响巴罗反射和化学反射敏感性的方法.
- 大脑自我调节和自主神经系统 (ANS) 活动之间的相互作用是复杂的,受呼吸模式的影响.
研究的目的:
- 为了研究呼吸驱动的振荡如何影响大脑自我调节和ANS活动之间的关系.
- 评估不同控制的呼吸速率对心血管和自主性参数的影响.
主要方法:
- 61名志愿者接受了动脉血压 (ABP),脑血速 (CBv),潮尾CO2 (EtCO2) 和呼吸速率的非侵入性测量.
- 通过转移函数分析 (相位转移和增益) 在非常低频 (VLF) 和呼吸频率 (BF) 范围内评估大脑自调.
- 通过巴罗反射灵敏度 (xBRS),心率变化率 (HRV) 和心血管合指标来评估ANS活动.
主要成果:
- 增加呼吸速率降低了EtCO2,降低了心血管合,并降低了全身血压控制 (较低的HRV和xBRS).
- 在VLF和BF的相位转移是由ANS指标调节的,而增益主要受到呼吸系参数的影响.
- 控制呼吸显著改变了大脑自我调节和ANS活动之间的关系.
结论:
- 较高的呼吸速率会对心血管合和ANS活动产生负面影响.
- 呼吸系统参数在调节大脑自我调节和呼吸系统之间的相互作用方面发挥着至关重要的作用.
- 在评估ANS-大脑自调节关系时,考虑呼吸系因素至关重要.
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