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Updated: May 5, 2026

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解密与dissulfidptosis相关的突变特征,化学敏感性和扩散大B细胞淋巴瘤的预后

Juanjuan Shang1, Bingyu Liu1, Xiaoli Zhou2

  • 1Department of Hematology, Shandong Provincial Hospital, Shandong University, No.324, Jingwu Road, Jinan, 250021, Shandong, China.

Journal of molecular medicine (Berlin, Germany)
|August 18, 2025
PubMed
概括

在许多癌症,特别是DLBCL中,与失硫素相关的基因 (DRG) 失调. 一个新的DRG风险评分准确预测DLBCL和其他癌症的预后和化学敏感性.

关键词:
化学敏感性 化学敏感性扩散大的B细胞淋巴瘤.脱硫脱症是一种脱硫脱症.突变的特征 突变的特征预测签名的预测签名

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...
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