在接受维持透析治疗的患者中,Dexcom G6 Pro和G7连续葡萄糖监测器的准确性
Leila R Zelnick1, Subbulaxmi Trikudanathan2, Yoshio N Hall1,3
1Kidney Research Institute and Division of Nephrology, University of Washington, Seattle, Washington, USA.
Diabetes technology & therapeutics
|August 18, 2025
概括
连续血糖监测器 (CGM) 对透析患者的准确性很高,G7系统的性能优于G6 Pro. 尽管绝对平均相对差异 (MARDs) 比非透析人群高,但CGM的使用得到了支持,用于评估透析患者的血糖.
科学领域:
- 脏病学和内分泌学
- 医疗器械技术 医疗器械技术
背景情况:
- 连续血糖监测器 (CGM) 为透析患者提供全面的血糖评估,克服了传统生物标志物的局限性,如糖化血红蛋白.
- 对间歇体积膨胀,干扰物质和透析效应的担忧使得在这个人群中采用较新的CGM版本变得复杂.
研究的目的:
- 评估Dexcom G6 Pro和G7连续血糖监测 (CGM) 系统与接受维持透析的患者自我监测血糖 (SMBG) 的准确性.
主要方法:
- 十二名糖尿病维持透析的参与者同时使用G6 Pro和G7 CGMs10天,使用Contour Next血糖计进行SMBG.
- 分析包括皮尔森相关性,平均绝对相对差异 (MARD),糖尿病技术协会 (DTS) 错误网格和CGM延迟时间评估.
主要成果:
- 观察到很高的相关性:G6 Pro/SMBG (0.87),G7/SMBG (0.88),以及G6 Pro/G7 (0.95).这些相关性是指G6 Pro/SMBG (0.87),G7/SMBG (0.88),以及G6 Pro/G7 (0.95).
- MARDs为21.2% (G6 Pro) 和16.7% (G7),分别提高到18.3%和13.5%,不包括一名参与者.
- 96.7% (G6 Pro) 和98.0% (G7) 的读数在临床上是可以接受的 (DTS区域A/B);与非透析人群相比,观察到延迟时间增加.
结论:
- 德克斯康G7和G6 ProCGM在透析患者中与SMBG有很高的相关性,G7表现优越.
- 虽然MARD比非透析人群高,但大多数读数在临床上是可以接受的,支持CGM用于血糖评估.
- 需要对滞后时间,传感器放置和干扰物质进行进一步的研究,以优化透析患者的CGM性能.
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