在稳定的精神分裂症住院患者中,sarcopenic肥胖和认知功能之间的关系
Yan Guo1, Jianfei Wu2, Xiuping Lei1
1Department of Psychiatry, the Zigong Affiliated Hospital, Southwest Medical University, Zigong, Sichuan, China.
PloS one
|August 18, 2025
概括
麻性肥胖症 (SO) 与精神分裂症患者的认知能力下降有关. 经修改的SOESPEN-M标准确定了SO与较低的认知分数相关,特别是在精神分裂症男性中.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
背景情况:
- 由于代谢问题和不活动,精神分裂症患者患型肥胖 (SO) 的风险更高.
- 需要进一步研究SO和精神分裂症认知衰退之间的联系.
研究的目的:
- 为了比较SOESPEN和SOESPEN-M标准之间的诊断一致性,用于SO.
- 评估SO与稳定的精神分裂症住院患者认知功能的关联.
主要方法:
- 228名稳定的精神分裂症住院患者使用SOESPEN和SOESPEN-M标准进行了SO的评估.
- 用蒙特利尔认知评估-中文版本 (MoCA-C) 测量认知功能.
- 多变量回归分析了SO和MoCA-C得分之间的关系.
主要成果:
- 根据这两个标准,SO的患病率为17.1%,与中度一致.
- 与非SO组相比,SO组的MoCA-C得分始终较低.
- 由SOESPEN-M定义的SO独立地与男性较低的MoCA-C得分有关.
结论:
- 在SOESPEN-M标准有效地识别与男性精神分裂症患者的认知障碍相关的SO.
- 在这个人群中,SO是影响认知功能的重要因素.
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