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Updated: Sep 11, 2025

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蛋白质语言模型伪相似性捕捉了体内B细胞选择和进化的特征

Daphne van Ginneken1, Anamay Samant2, Karlis Daga-Krumins1

  • 1Center for Translational Immunology, University Medical Center Utrecht, Lundlaan 6, Utrecht 3584EA, The Netherlands.

Briefings in bioinformatics
|August 18, 2025
PubMed
概括

蛋白语言模型 (PLMs) 可以预测体内B细胞选择特征,包括体质突变和同型使用. 这些模型通过分析抗体序列数据,为抗体发现和工程提供了潜力.

关键词:
B 细胞 B 细胞 B 细胞抗体是对抗体的重要组成部分.蛋白质语言模型的模型曲目 曲目 曲目 曲目身体上的超突变.

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