在接受食道切除术的食道癌患者的术前和术后运动和营养治疗:一项前性干预研究
Annals of nutrition & metabolism
|August 18, 2025
概括
对食道癌患者的术后运动和营养治疗是安全和可行的,改善身体功能. 然而,骨肌肉质量 (SMM) 在手术后下降,这表明需要进一步研究优化这种干预措施.
科学领域:
- 在瘤学瘤学.
- 手术营养是指手术营养.
- 运动生理学 运动生理学
背景情况:
- 经过手术的食道癌患者经常经历显著的骨肌肉质量 (SMM) 损失.
- 优化外科手术期间的干预措施对于改善食道切除术后患者的治疗结果至关重要.
研究的目的:
- 评估一个联合的术后运动和营养治疗计划的安全性和可行性.
- 探索这种干预对食道癌患者骨肌肉质量 (SMM) 和身体功能的影响.
主要方法:
- 一项前性研究,涉及36名预定进行治愈性食道切除术的患者.
- 干预包括3周的术前和4周的术后运动和营养治疗.
- 骨肌肉质量 (SMM) 和身体功能在干预前,手术前和手术后1个月被评估.
主要成果:
- 干预是安全的和可行的,完成率为94.4%,没有严重的不良事件.
- 骨肌肉质量 (SMM) 在手术前增加,但从基线到手术后1个月减少了10.1%.
- 手术后的身体功能显著改善,在维持热量摄入和活动的患者中观察到较低的SMM损失.
结论:
- 术后运动和营养治疗对于食道癌症患者来说是安全和可行的.
- 该干预导致了手术前SMM和手术后身体功能的改善,但手术后SMM总体下降.
- 需要进一步的研究,以优化干预措施的有效性,防止手术后的SMM下降.
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