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Updated: Sep 11, 2025

A Protein Microarray Assay for Serological Determination of Antigen-specific Antibody Responses Following Clostridium difficile Infection
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Clostridioides difficile毒素A和毒素B通过依赖葡萄糖转酶的活性抑制毒素特异性适应性免疫反应

Jeffrey R Maslanka1, Jennifer A Londregan2, Joshua E Denny3

  • 1Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Immunology Graduate Group, University of Pennsylvania, Philadelphia, PA, USA.

Mucosal immunology
|August 18, 2025
PubMed
概括

艰难毒素A和B阻碍了适应性免疫力. 它们的葡萄糖转移酶活性会损害免疫反应,这可能解释了复发的C. difficile感染.

关键词:
克洛斯特里迪奥伊德斯困难菌在 IgAA 里面.肠道 CD4 T 细胞粘膜免疫学 粘膜免疫学毒素是一种毒素.

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