协生酸奶与纳米颗粒捕获的米半纤维素,用于立即的益生菌支持和益生菌输送
Shaymaa A Ismail1, Bahgat Fayed2, Hoda S El-Sayed3
1Department of Chemistry of Natural and Microbial Products, Pharmaceutical and Drug Industries Research Institute, National Research Centre, 33 El Bohouth St., Dokki, 12622, Giza, Egypt.
NPJ science of food
|August 18, 2025
概括
这项研究开发了一种使用大米半纤维素化物 (RSHH) 的新型共生酸奶,用于增强益生菌支持和持续的益生菌递送. 该RSHH证明了抗氧化和抗癌特性,改善了小鼠的肠道细菌生长和安全性.
科学领域:
- 食品科学 食品科学 食品科学
- 生物技术是生物技术.
- 营养保健品 营养保健品
背景情况:
- 协生食物结合益生菌和益生菌来增强健康益处.
- 草半纤维素化物 (RSHH) 是益生菌氧化糖的潜在来源.
- 开发有效的益生菌传递系统对于功能性食品至关重要.
研究的目的:
- 开发一种新型的共生酸奶,增添了自由的和PLGA捕获的RSHH.
- 评估RSHH的益生菌,抗氧化剂和抗癌性质.
- 评估共生酸奶在老鼠中的生物安全性和有效性.
主要方法:
- 草的酶性水解以获得RSHH.
- 关于RSHH的组成,抗氧化活性和抗癌作用的表征.
- 将RSHH封装成PLGA纳米粒子.
- 在酸奶中加入自由和被困的RSHH.
- 在老鼠中评估益生菌的生长,稳定性和生物安全性.
主要成果:
- RSHH富含有显著抗氧化剂和抗癌活性的氧化氧化糖.
- RSHH增强了Lactiplantibacillus paraplantarum和Bifidobacterium bifidum的生长. 这两种类型的细菌的生长.
- PLGA纳米粒子有效地封装了具有理想特征的RSHH.
- 与自由和被困RSHH的协生酸奶在20天内显示出更好的性能.
- 在老鼠身上进行的生物安全测试证实没有副作用,并且改善了脂质配置文件.
结论:
- 使用RSHH的新型共生酸奶配方提供了益生菌和益生菌的双重输送.
- PLGA封装增强了前生物的稳定性和功能性食品中的传递.
- 这种双交付系统为开发先进的功能性食品提供了一个有希望的方法.
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