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Updated: Sep 11, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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Published on: March 15, 2024

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SPI1转录激活TXNRD1以保护热囊细胞免受铁灭

Tiantian Chen1, Ruxiu Ge1, Jie Bai1

  • 1Department of Obstetrics, Shenzhen Maternal and Child Healthcare Hospital, No. 3012, Fuqiang Road, Futian District, Shenzhen City, Guangdong Province, 518017, China.

Reproductive sciences (Thousand Oaks, Calif.)
|August 18, 2025
PubMed
概括

铁素还原酶1 (TXNRD1) 在孕前症 (PE) 中降低调节,导致胎盘细胞铁亡. 抑制TXNRD1或其激活剂SPI1可以保护人免受铁,为PE的病原性提供了洞察力.

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