综合疾病管理,在预防和控制之间进行最佳的努力分配
Mathieu Bonneau1, Nathalie Mandonnet2, Carine Marie-Magdeleine2
1ASSET UR0143, INRA, 97170, Guadeloupe, Petit-Bourg, France. mathieu.bonneau@inrae.fr.
Scientific reports
|August 18, 2025
概括
预防和控制疾病的平衡对于有效管理至关重要. 这项研究提出了一个数学模型,以优化这些努力,确保经济上可行的策略,对疾病,如胃肠道线虫在小反动物.
科学领域:
- 兽医流行病学 兽医流行病学
- 数学建模的数学建模
- 疾病管理 疾病管理
背景情况:
- 预防和控制是疾病管理的关键策略,但平衡它们的实施是具有挑战性的.
- 控制工作可能会延迟,导致不可逆转的损害.
- 在预防和控制之间优化资源配置是一个实际的问题.
研究的目的:
- 开发一个数学模型来平衡预防和控制努力与预期的疾病损失.
- 为了获得最佳预防和控制策略的分析解决方案.
- 将框架应用于小反动物的胃肠道线虫管理.
主要方法:
- 制定一个数学模型来衡量预防和控制的有效性与疾病的概率.
- 分析解决方案的推导,以实现最佳的努力分配.
- 应用和插图使用小反动物的胃肠道线虫的数据.
主要成果:
- 最佳的预防和控制努力取决于每个策略的相对有效性和疾病发生的概率.
- 计算的最低抗虫疗效,以提供经济有效的治疗.
- 确定了监测的最佳成本效益和综合管理策略的最大成本.
结论:
- 开发的框架提供了一种经济评估新疾病管理策略的方法.
- 为优化实际预防和控制工作提供决策规则.
- 帮助设计经济上可行的牲畜疾病管理实践.
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