伊朗结核病老年人药物坚持的决定因素的结构模型
Somayeh Hassani1, Farahnaz Mohammadi Shahboulagi2, Mahshid Foroughan3
1Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. hassani27961@gmail.com.
BMC public health
|August 19, 2025
概括
老年结核病患者的药物坚持是复杂的,个人因素显著影响结果. 了解这些决定因素对于有效的结核病控制策略在老龄化人口中至关重要.
科学领域:
- 公共卫生 公共卫生
- 老年学是一门学科.
- 传染性疾病 传染性疾病
背景情况:
- 药物坚持对于成功治疗结核病至关重要.
- 结核病的老年人表现出更高的不服药率,造成治疗失败和社区传播的风险.
- 越来越多的老年人群需要专注的策略来改善结核病药物治疗的坚持.
研究的目的:
- 开发和测试伊朗结核病老年人药物坚持的决定因素的结构模型.
- 确定关键的个人,人际和组织之外的因素,这些因素影响了这个人口中的药物坚持.
主要方法:
- 采用了混合方法,顺序的探索设计.
- 通过德尔菲方法,定性数据为专家通过德尔菲方法识别有影响力的变量提供了信息.
- 一个结构方程模型分析了305名老年结核病患者及其照顾者的数据,使用验证的问卷.
主要成果:
- 44.92%的老年结核病患者的药物服药程度较低.
- 个人因素 (例如,提醒,动机,副作用) 是最重要的直接预测因素 (62%的总效果).
- 人际关系和组织外因素间接预测了通过个人因素的坚持.
结论:
- 老年结核病患者的药物坚持是一个复杂的,多维的问题.
- 个人因素起着主导作用,强调了患者在坚持治疗中的核心作用.
- 开发的结构模型为针对性干预和结核病控制政策制定提供了框架.
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