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Updated: Sep 11, 2025

Time-Lapse 2D Imaging of Phagocytic Activity in M1 Macrophage-4T1 Mouse Mammary Carcinoma Cells in Co-cultures
10:23

Time-Lapse 2D Imaging of Phagocytic Activity in M1 Macrophage-4T1 Mouse Mammary Carcinoma Cells in Co-cultures

Published on: December 14, 2019

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子宫内膜癌和瘤相关巨细胞之间的代谢相互作用:乳酸诱导的M2极化增强了瘤进展

Xiaodie Liu1,2, Heming Sun3, Jing Liang1

  • 1Department of Obstetrics and Gynecology, China-Japan Friendship Hospital, Beijing, 100029, China.

Journal of translational medicine
|August 19, 2025
PubMed
概括

子宫内膜癌细胞产生乳酸,促进M2巨细胞的两极化和瘤的生长. 阻断IL-6信号抑制了这一过程,为子宫内膜癌提供了潜在的治疗策略.

关键词:
有氧糖溶解是有氧的.血管新生的产生.这是子宫内膜癌的癌症.皮质 - 介质细胞过渡.在IL-6的研究中,IL-6被认为是IL-6的基因.乳酸盐是一种乳酸盐.代谢重新编程的代谢.与瘤相关的巨细胞.

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