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对不同纳米粒子的物理化学和生物活性特性进行比较,这些纳米粒子是基于酸基改性水泥的
Silsupa Saingern1, Naruporn Monmaturapoj2, Chanakarn Sinsareekul3
1Department of Operative Dentistry, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
BMC oral health
|August 19, 2025
概括
将ZrO2,TiO2和酸 (HAP) 等纳米颗粒添加到酸基水泥 (CSC) 中,显著减少了定时间,并证明了生物活性潜力. 虽然一些修改增加了溶解度,但所有修改都保持在牙科应用的可接受范围内.
科学领域:
- 生物材料科学 生物材料科学
- 牙科材料科学 牙科材料科学
- 纳米技术在医学中的应用
背景情况:
- 基于酸的水泥 (CSCs) 在牙科中被广泛使用.
- 研究纳米粒子添加剂可以增强CSC属性.
- 探索了ZrO2,TiO2和酸 (HAP) 的纳米粒子.
研究的目的:
- 评估ZrO2,TiO2和HAP纳米粒子对CSC物理化学和生物活性特性的影响.
- 确定用于水泥改造的最佳纳米粒子度 (5%和10%).
主要方法:
- 用纳米粒子 (n-ZrO2,n-TiO2,n-HAP) 修改的CSCs被制备出来.
- 根据ISO标准测试了定时间,压力强度和可溶性.
- 使用扫描电子显微镜与能量分散光谱 (SEM-EDS) 评估了生物活性.
主要成果:
- 所有纳米粒子添加剂显著减少了CSC设置时间.
- ZrO2纳米颗粒提升了早期的压力强度,而HAP和TiO2则表现出不同的效果.
- 在大多数修饰组中,溶解度增加,但仍保持在可接受的范围内.
- SEM-EDS证实了亚酸盐的形成,表明生物活性,Ca/P比率与对照组相似.
结论:
- 纳米颗粒的结合加快了CSC的设置时间,并显示了生物活性潜力.
- ZrO2纳米颗粒提供早期强度增强,而其他纳米颗粒影响性能不同.
- 修改后的CSC在牙科应用中表现出有希望的特性,可溶性在可接受的范围内.
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