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Updated: May 1, 2026

Assessment of Vascular Regeneration in the CNS Using the Mouse Retina
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通过AAV介导的STC-1表达减轻神经炎症,并在退行性视网膜病变中保持视觉功能

Yange Wang1, Siyu Li1, Chenxu Zhang1

  • 1Department of Ophthalmology, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Henan Eye Hospital and Henan Key Laboratory of Ophthalmology and Visual Science, Zhengzhou, 450003, China.

Journal of translational medicine
|August 19, 2025
PubMed
概括

斯坦尼奥卡尔辛-1 (STC-1) 基因疗法在治疗视网膜退化 (RD) 方面表现有前途. 在小鼠模型中,过度表达STC-1保留了视网膜结构,并通过减少炎症和氧化应激来改善视力.

关键词:
行为行为行为.氧化应激是一种氧化应激.视网膜退行症 视网膜退行症视觉功能 视觉功能 视觉功能

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Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
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