中国草药治疗失眠:一个系统的审查和网络元分析
Weiwei Li1, Qinxuan Wang2, Chun Dang3
1Department of General Surgery, Chengdu Integrated Traditional Chinese Medicine and Western Medicine Hospital, Chengdu, China.
Medicine
|August 19, 2025
概括
中国草药显示出作为治疗失眠的有效和安全替代品的承诺,可能会超过传统药物. 这一系统性审查强调了对睡眠质量和安全的最佳表现的草药.
科学领域:
- 综合医学是一个整体的医学.
- 药理学 药理学是指药理学的学科.
- 睡眠科学 睡眠科学
背景情况:
- 失眠是一个重要的全球健康问题,带来了大量的疾病负担.
- 常规的药物治疗失眠有局限性和不良影响.
- 中国草药 (CHM) 是一个潜在的替代品,由于历史的使用和多方面的行动.
研究的目的:
- 系统地审查和综合有关治疗失眠的CHM疗法的有效性和安全性的证据.
- 为了比较各种CHM的性能,并将其与传统治疗进行对比.
- 确定在睡眠质量,有效性和安全性方面具有优异结果的特定CHM.
主要方法:
- 一个系统的审查和贝叶斯网络对186个随机对照试验 (RCT) 的元分析,遵循PRISMA-NMA指南.
- 在主要数据库 (MEDLINE,Cochrane,EMBASE,Wanfang,CNKI) 和灰色文献中进行的搜索.
- 主要结局包括匹兹堡睡眠质量指数 (PSQI) 评分,临床有效率率和不良事件发生率.
主要成果:
- 改善PSQI得分的顶级治疗方法是:guipi脱剂,shenqi schisandra片,chaihu longgu muli脱剂 (CLMD),suanzaoren,以及wuling囊.
- 观察到的最高的有效率是用longdan xiegan,CLMD,guipi,Huanglian Wendan和chaihu shugan粉.
- 对 jieyu 药丸,特拉佐和 CLMD 确定了优异的安全性概况;大多数 CHM 显示出比传统药品更好的安全性.
结论:
- 某些中国草药为失眠提供了有效和安全的治疗选择.
- 这些发现表明,CHM可能会减少对传统药理干预的依赖.
- 进一步的研究可能会验证这些草药替代品在失眠管理中广泛临床使用.
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