探索性研究关于白细胞体和精神障碍在精神病室门诊患者之间的关系
Fumi Akasaka1, Kuni Akasaka1, Kazutake Okada2
1Akebono Clinic, 26-1 Kaminakasone, Ishinomaki, Miyagi, Japan.
白细胞病,或高白细胞计数,在精神病室门诊患者中比一般人群更为常见. 这种升高的白细胞计数在患有精神分裂症谱系,双相情绪和强迫症患者中尤其普遍.
科学领域:
- 精神病学是一个精神病学.
- 血液学 血液学 血液学
- 临床医学 临床医学
背景情况:
- 在一些精神疾病中注意到炎症性细胞因子和白细胞 (WBC) 的升高.
- 精神病室门诊患者白细胞病的患病率和临床意义尚未得到充分确立.
研究的目的:
- 调查精神病室门诊患者中白细胞病的流行情况.
- 检查白细胞症与特定精神疾病之间的关联.
- 评估白细胞症在精神病室门诊护理中的相关性.
主要方法:
- 在Akebono诊所 (1120名精神病室门诊患者) 进行的回顾性研究 (2022年10月 - 2023年9月).
- 收集的数据包括年龄,性别,DSM-5-TR分类,以及最高/最低的白细胞计数.
- 白血细胞症定义为绝对白血细胞计数>10,000个细胞/μL.
主要成果:
- 16.7%的门诊患者至少有一次表现出白细胞瘤.
- 这种患病率明显高于一般日本人口 (P < .001).
- 在精神分裂症,双相,强迫症和人格障碍患者以及中年人群 (30-69岁) 中,白血细胞症超过20%.
结论:
- 与普通人群相比,精神病室门诊患者中白血细胞病的发生频率明显高.
- 特定的精神疾病,包括精神分裂症谱系,双相情绪和强迫症,显示白细胞瘤的患病率更高.
- 这些发现强调了监测精神病治疗中的WBC计数的潜在临床相关性,特别是在某些患者群体和年龄人口统计学方面.
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