代谢功能障碍相关的脂肪性肝病与心血管疾病之间的关联:新的视角
Qinyi Zhou1,2, Wang Liu3, Dan Zhou1
1Department of Cardiology, The Affiliated Nanhua Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
与代谢功能障碍相关的脂肪性肝病 (MASLD) 和心血管疾病 (CVD) 的研究正在迅速扩大. 炎症和肠道微生物群等关键因素正在成为理解它们联系的关键因素.
科学领域:
- 肝病学和心脏病学.
- 代谢障碍 代谢障碍 代谢障碍
- 图书统计分析 图书统计分析
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD),以前称为非酒精性脂肪性肝病 (NAFLD),与全身胰岛素抵抗和代谢功能障碍有关.
- MASLD/NAFLD显著增加患心血管疾病 (CVD) 的风险.
- 了解MASLD/NAFLD和CVD不断变化的研究环境对于推进患者护理至关重要.
研究的目的:
- 对MASLD/NAFLD和CVD之间的关联进行文献分析.
- 概述这个领域的历史进展,当前的研究热点和未来的趋势.
- 确定关键的致病因素和潜在的治疗点.
主要方法:
- 使用Citespace (版本6.3.1) 的文献计量分析.
- 关于MASLD/NAFLD和CVD的文学综合评论.
- 确定研究趋势,影响因素和新兴领域.
主要成果:
- 在过去的19年中,观察到关于MASLD/NAFLD和CVD的研究出版物显著增加.
- 已经确定的风险因素,如阿氨酸转移酶 (ALT) 和代谢综合征仍然很重要.
- 诸如炎症,肠道微生物群和氧化应激等新兴因素在MASLD的发病过程中越来越突出.
结论:
- 这项研究强调了日益增长的研究兴趣和深入了解MASLD/NAFLD-CVD相互关系.
- 新出现的因素为MASLD/NAFLD的病理生理学提供了新的视角.
- 这一分析为未来的研究方向和两种疾病的预防策略提供了洞察力.
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