在非性状态中出现周期性成像异常:一个系统的综述和元分析,比较磁共振成像和计算机断层扫描 perfusion
Pilar Bosque-Varela1,2, Giorgi Kuchukhidze1,2, Wiebke Hahn3
1Department of Neurology, Christian Doppler University Hospital, Centre for Cognitive Neuroscience, Member of the European Reference Network EpiCARE, Paracelsus Medical University of Salzburg, Salzburg, Austria.
计算机断层扫描输液 (CTP) 在非性状态 (NCSE) 中检测到比标准MRI更多的周周性异常. 动脉旋转标记MRI也显示了NCSE的高检测率.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 神经成像是一种神经成像.
背景情况:
- 非性状态 (NCSE) 呈现出诊断方面的挑战.
- 周期性异常是NCSE的关键指标.
- 准确检测这些异常对于及时诊断和管理至关重要.
研究的目的:
- 为了比较磁共振成像 (MRI) 和计算机断层扫描输液 (CTP) 在检测NCSE患者的周周异常时的疗效.
- 评估不同MRI序列的检测率,包括动脉旋转标记 (ASL),用于NCSE.
主要方法:
- 在五个数据库中进行系统的文献搜索,截至2025年2月.
- 在NCSE中纳入报告周转眼MRI异常 (PMA) 或脑 perfusion异常 (CPA) 的研究.
- 使用随机效应模型进行比例的元分析,并进行子组分析和元回归.
主要成果:
- 分析了19项研究 (562名MRI患者,72名CTP患者).
- 与传统MRI (50.0%) 相比,CTP显示了较高的聚合检测率 (79.3%).
- 动脉旋转标记MRI显示高检测率 (88.8%),与CTP相比没有显著差异.
结论:
- 在NCSE中,CTP提供了比常规MRI更高的围性异常检测率.
- 动脉旋转标记MRI是NCSE诊断评估的一个有希望的序列.
- 虽然MRI对于病因澄清至关重要,但其PMA检测能力随着使用的序列而有很大变化.
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