结合色彩成像与常规白光结肠镜检测结肠直肠多
Jun Watanabe1,2,3, Takeshi Kanno4,5, Eiichi Kakehi6
1Division of Community and Family Medicine, Jichi Medical University, Tochigi, Japan.
The Cochrane database of systematic reviews
|August 19, 2025
概括
与白光成像 (WLI) 相比,链接色彩成像 (LCI) 在结肠镜检查期间略有提高了腺瘤检测率 (ADR) 和聚检测率. 这一系统性审查发现LCI是安全的,不增加不良事件.
科学领域:
- 胃肠病学和内镜检查
- 预防癌症 预防癌症
- 医学成像技术 医学成像技术
背景情况:
- 通过结肠镜检测结肠直肠多的早期检测对于预防结肠镜后结肠直肠癌 (PCCRC) 至关重要.
- 腺瘤检测率 (ADR) 的1%增加与PCCRC发病率的3%降低相关.
- 连接色彩成像 (LCI) 与白光成像 (WLI) 相比,提供了增强的色彩对比,可能改善ADR.
研究的目的:
- 系统地审查和评估LCI与WLI结肠镜的益处和危害.
- 评估LCI在检测结直肠多瘤的有效性,用于查,症状评估和监测.
- 综合随机对照试验 (RCT) 关于LCI对多检测和患者安全的影响的证据.
主要方法:
- 进行了对RCT进行系统审查和元分析,比较LCI和WLI结肠镜.
- 搜索了多个数据库 (CENTRAL,MEDLINE,Embase,ClinicalTrials.gov) 截至2025年5月.
- 包括16个RCT与12836名参与者;使用Cochrane RoB 2工具评估偏差风险.
主要成果:
- 高确定性证据表明,与WLI相比,LCI稍微增加了ADR (RR 1.18) 和聚检测率 (RR 1.14).
- 中等确定性证据表明,LCI可能会增加每位参与者检测的状状病变 (RR 1.61) 和腺瘤 (MD 0.18).
- 没有观察到需要医疗治疗的不良事件显著增加 (中等确定性证据).
结论:
- 结合色彩成像 (LCI) 在结肠镜检查期间在腺瘤和多检测方面提供了轻微但显著的改善.
- 与WLI相比,LCI似乎是一种安全的成像模式,没有增加不良事件的风险.
- 进一步的研究应该集中在临床上重要的结果,如PCCRC发病率,以充分确定LCI的长期影响.
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