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职业作为慢性病进展的危险因素:回顾性队列研究
Daisuke Takada1,2, Susumu Kunisawa1, Akira Kikuno3
1Department of Healthcare Economics and Quality Management, Graduate School of Medicine, Kyoto University, Yoshida Konoe-cho, Sakyo-ku, Kyoto City, Kyoto, Japan.
Journal of occupational health
|August 19, 2025
概括
职业类型影响慢性病 (CKD) 进展风险. 某些行业显示,员工估计的球过率 (eGFR) 降低的风险较低,这表明社会经济因素对脏健康起着作用.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 职业健康 职业健康 职业健康
- 公共卫生 公共卫生
背景情况:
- 慢性病 (CKD) 的病因通常是未知的.
- 社会经济地位越来越被认为是CKD进展的一个因素.
研究的目的:
- 调查职业分类与CKD进展风险之间的关联.
- 为了在18个不同的职业群体中比较CKD进展风险.
主要方法:
- 利用日本的年度健康检查和医疗保险索赔数据 (2012年4月至2016年3月).
- 主要结局被定义为估计膜过率 (eGFR) 降低>30%.
- 采用了考克斯的比例风险模型,对多个健康和人口变量进行调整.
主要成果:
- 分析了239,506名员工;1,736名 (0.7%) 在平均2.8年的随访期间经历了超过30%的EGFR下降.
- 与制造业相比,五个行业类别在调整后显示了eGFR下降的风险较低.
- 这些行业包括信息/通信,运输,住宿/食品服务,个人服务和医疗保健/福利.
结论:
- 职业类型是CKD进展风险的重要决定因素.
- 特定行业可能提供预防功能衰退的保护因素.
- 需要进一步的研究来阐明机制和因果关系.
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