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患者和一级亲属对预测和预防炎症性肠病的看法 - 一项跨国调查
Ana Catarina Bravo1, Sara Godt Christensen2, Mette Julsgaard2,3,4
1Division of Gastroenterology, Hospital Beatriz Ângelo, Loures, Portugal.
United European gastroenterology journal
|August 19, 2025
概括
大多数有炎症性肠病 (IBD) 风险的人愿意接受预测测试和预防性干预. 对微创试验和生活方式改变的接受度很高,对药物有一定的开放性.
科学领域:
- 胃肠道学和免疫学
- 预测医学是一种预测医学.
- 公共卫生 公共卫生
背景情况:
- 确定预测炎症性肠病 (IBD) 发病的生物标志物正在取得进展.
- 关于有风险的个体对预测测试和预防干预的意愿,我们知之甚少.
研究的目的:
- 评估预测测试和预防干预措施在IBD风险较高的人群中的接受度.
- 确定影响IBD预测和预防决策的因素.
主要方法:
- 一项匿名电子调查分发给有IBD风险的儿童的父母和IBD患者的一级亲属.
- 该调查评估了预测测试,预防干预和影响变量的接受度.
主要成果:
- 1327名参与者的85%愿意接受预测测试,更喜欢进行血液,便或唾液测试.
- 98%接受了预防性干预措施,支持饮食改变,运动和益生菌.
- 免疫抑制治疗的接受程度因疗效,难度和风险而异.
结论:
- 大多数受访者更喜欢微创性预测测试和非药物预防措施.
- 超过三分之一的人会考虑使用免疫抑制药物来预防IBD发病.
- 疾病知识和生活质量认知显著影响IBD预测和预防策略的偏好.
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