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在同性别女性夫妇使用伴侣的卵子与自己的卵子进行体外受精结果的比较:系统性审查

Elizabeth Choong¹, Phoebe Barry², Susan Bewley³

¹Medical School, University of Leeds, Leeds, UK.

Journal of homosexuality

|August 19, 2025

概括

相反的试管婴儿 (共同试管婴儿) 与其他方法相比,显示出更高的怀孕和出生率,但出生体重较低. 迫切需要更多的研究来评估安全性,并为考虑联合IVF的夫妇制定指南.

科学领域:

生殖医学生殖医学
在体外受精过程中受精.
孕产妇和胎儿医学孕产妇和胎儿医学

背景情况:

互惠试管婴儿 (共同试管婴儿) 是女性同性伴侣日益增长的选择.
没有系统性审查将共同IVF结果与使用自己的卵子进行IVF的结果进行比较.
本次审查解决了对比生殖结果数据中的这一差距.

研究的目的:

系统地审查和比较母亲和儿童的结果.
将共同IVF与使用自己的卵子 (异性恋,女同性恋,单身女性,跨性别男性) 的IVF进行比较.
确定共同试管婴儿安全性和有效性的研究缺口.

主要方法:

在遵守PRISMA指南的基础上进行系统审查.
在Embase,Medline,PsycInfo,Scopus,Cochrane数据库中搜索到2024年11月.
五项回顾性队列研究 (2021-2023) 的元分析.

主要成果:

联合试管婴儿证明了更高的临床怀孕和活产率,而不是IUI,异性恋试管婴儿,单身女性和自己卵的女同性恋试管婴儿.
同时IVF与较低的出生体重有关.
在一项联合IVF研究中,注意到高血压疾病和妊娠糖尿病的增加率.

结论:

联合试管婴儿提供了更好的怀孕和出生率,但需要监测对母亲和婴儿的不良结果.
关于卵巢过度刺激综合征和儿童发育等关键结果的数据有限.
迫切需要进行更大规模,多样化的研究,以告知共同IVF的安全性,指导方针和患者咨询.

关键词:

一个女同性恋的女同性恋者.罗帕 (ROPA) 是一个字母.在共同IVF中进行IVF.怀孕怀孕怀孕怀孕怀孕互惠的试管婴儿试管婴儿 (IVF) 是一个互惠的方法.同性恋女性夫妇同性恋女性夫妇分享的IVF是共享的IVF.

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