在肝胃肠道外科诊所内镜前的HCV查:深度C内科研究
André-Jean Remy1, Serge Bellon2, Ryad Smadhi3
1Service d'Hépato-gastro-entérologie, Centre Hospitalier, Perpignan, France.
Journal of viral hepatitis
|August 19, 2025
概括
在40岁以上的成年人内镜检查前对肝炎C病毒 (HCV) 进行系统查是可行的,并且得到了很好的接受. 这种方法可以识别出大量的积极病例,以便及时管理和治疗.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 肝炎C病毒 (HCV) 血清流行率随着年龄的增长而增加.
- 目前法国的指导方针为普遍的HCV查提供了相互矛盾的建议.
- 在老年人群中进行有针对性的查可能会提高检测率.
研究的目的:
- 评估40岁及以上人群内镜前HCV查的可行性和可接受性.
- 确定该人口群中的HCV患病率是否超过一般人口的患病率 (0.86%).
- 评估前内镜查在识别和管理HCV病例中的有效性.
主要方法:
- 一项前性研究涉及490名40岁以上的患者,他们在法国八家医院接受内镜检查.
- 向所有符合条件的患者提供HCV血清学.
- 收集的数据包括血清学接受率和表现率,患者人口统计,风险因素和病毒载荷测试.
主要成果:
- 查HCV是高度可行的 (97.4%的接受率,97.6%的性能).
- 肝炎病毒病毒阳性率为6%,明显高于一般人群.
- 确定的风险因素包括药物使用 (19名患者),输血史 (6名患者) 和来自特有国家 (5名患者) 的来源.
- 在28名病毒负载阳性患者中,有11名患者接受治疗.
结论:
- 在内镜检查之前,对40岁及以上的患者进行系统的HCV查是可行的,并且得到了很好的接受.
- 这一策略有效地识别了大量以前未被诊断的HCV感染.
- 在内镜前的查有助于及时管理和启动HCV患者的治疗.
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