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Updated: Sep 10, 2025

Uracil-DNA Glycosylase Assay by Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry Analysis
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Published on: April 22, 2022

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发现和描述Uracil衍生品,针对UHRF1的设置和戒指域

Ifigeneia Akrani1, Danai Driva1, Efstratios Tsakalidis1

  • 1Division of Pharmaceutical Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece.

Journal of chemical information and modeling
|August 19, 2025
PubMed
概括

研究人员确定了基于 uracil 的新型化合物,通过准其 SRA 域来调节 UHRF1 瘤基因. 这些化合物通过减少癌细胞中的全球DNA甲基化来显示出表观遗传疗法的潜力.

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