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Updated: Sep 10, 2025

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
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Published on: February 16, 2022

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氧化通过控制氧气可用性来促进氨酸N-降解蛋白质分解

Haeun Kim1,2, Ya-Min Tian1,2, Peter J Ratcliffe1,2,3

  • 1Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, United Kingdom.

Proceedings of the National Academy of Sciences of the United States of America
|August 19, 2025
PubMed
概括

氧化 (NO) 通过N-降解通路间接调节蛋白质稳定性,通过调节2-氨基乙乙醇二氧化酶 (ADO) 的氧气可用性. 这种机制将氧气供应和细胞呼吸与信号通路联系起来.

关键词:
在N-degron中降解.缺氧 缺氧是指缺氧的情况.氧化氧化的使用方法氧气 氧气 氧气 氧气蛋白质溶解过程中的蛋白质溶解.

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