在人体疲劳性腹膜工作期间,腹膜的高血压和代谢反射反应
Megan L Lance1, Christina D Bruce1, Madison M Coyle1
1Centre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, University of British Columbia, Kelowna, BC, Canada.
The Journal of physiology
|August 19, 2025
概括
隔膜血液流量随着运动强度的增加而增加,但与疲劳或灵感肌肉代谢反射无关. 这种反应在男性和女性中是相似的,挑战了以前关于隔膜血流调节的性别差异的假设.
科学领域:
- 生理学 生理学 生理学
- 呼吸系统医学 呼吸系统医学
- 运动科学 运动科学
背景情况:
- 吸气肌代谢反射 (IMM) 在吸气压力值负荷 (ITL) 期间增加呼吸肌血流.
- IMM对隔膜血流 (Q̇di) 和人类疲劳的具体影响尚不清楚.
- 与男性相比,女性可能表现出减弱的IMM,这表明在隔膜血流调节和疲劳方面存在潜在的基于性别的差异.
研究的目的:
- 在健康的男性和女性中,调查腹膜高血,代谢反射敏感性和在ITL期间腹膜疲劳之间的关系.
- 为了确定腹膜血流反应和疲劳的发展在疲劳的灵感负荷期间性别之间是否有所不同.
主要方法:
- 健康的男性和女性接受了6分钟的ITL在80cmH2O.
- 与对比度增强的超声波测量了Q̇di在各种任务完成点.
- 代谢反射激活 (ΔMAP) 和隔膜疲劳 (ΔPdi,tw) 分别通过血压变化和跨隔膜抽压力进行评估.
主要成果:
- 隔膜高血压 (ΔQ̇di) 与相对运动强度 (%Pdi,max) 有正相关性.
- 在隔膜高血症和代谢反射敏感性 (ΔMAP) 或隔膜疲劳 (ΔPdi,tw) 之间没有发现显著的关系.
- 在IMM激活,隔膜疲劳或隔膜高血症方面没有观察到基于性别的差异,尽管相对运动强度相似.
结论:
- 在ITL期间的隔膜高血压主要与相对的运动强度有关,而不是代谢反射敏感性或疲劳.
- 与假设相反,在隔膜高血压,代谢反射反应或疲劳方面没有发现基于性别的差异.
- 这些发现表明,在疲劳的启发性负载期间,隔膜血流调节在男性和女性之间是相似的.
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