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Updated: Sep 10, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
07:16

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

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氨基林受体子单元相互作用由激动剂调节,并决定信号传递

Sandra E Gostynska1, Jordan A Karim1, Bailee E Ford1

  • 1Department of Biochemistry and Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

Science signaling
|August 19, 2025
PubMed
概括

氨基林受体 (AMYRs) 对于代谢调节和糖尿病药物开发至关重要. 这项研究揭示了AMYR亚单元与激动剂的相互作用如何动态变化,影响cAMP信号传递并提供新的治疗点.

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Studying the Hypothalamic Insulin Signal to Peripheral Glucose Intolerance with a Continuous Drug Infusion System into the Mouse Brain08:32

Studying the Hypothalamic Insulin Signal to Peripheral Glucose Intolerance with a Continuous Drug Infusion System into the Mouse Brain

Published on: January 4, 2018

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