青少年时期的疼痛和自杀倾向:丹麦国家队列研究
Liv Mathilde Pampiri1,2, Carsten Hjorthøj2,3, Olivia Kirtley4
1Danish Research Institute for Suicide Prevention, Copenhagen Research Center for Mental Health (CORE), Mental Health Center Copenhagen, Copenhagen, Denmark.
Pain
|August 19, 2025
概括
11岁儿童频繁疼痛与18岁时自杀想法和尝试的风险更高有关. 精神病学诊断部分解释了这种联系,强调疼痛是预防青少年自杀的潜在目标.
科学领域:
- 青少年健康 青少年健康
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 疼痛是已知的青少年自杀倾向的危险因素.
- 了解早期疼痛与青少年自杀倾向之间的长期关联至关重要.
研究的目的:
- 为了检查11岁时疼痛和18岁时自杀倾向之间的联系.
- 评估精神病诊断在这种协会中的调解作用.
主要方法:
- 利用了来自丹麦国家出生队列 (DNBC) 11年和18年随访的数据.
- 在11岁时分析了自我报告的疼痛 (头部,胃,部,背部) 作为暴露.
- 评估了自杀念头,自我报告和医院记录的自杀企图,以18岁为结果.
- 采用多项逻辑回归和调度分析,对共变量和采样重量进行调整.
主要成果:
- 在28465名11岁儿童中,有13.5%的人报告经常疼痛.
- 频繁的疼痛与自杀念头 (aRRR=1.6) 和自杀企图 (aRRR=2.4) 的风险增加有关.
- 在11岁时报告3个以上疼痛部位显著增加了自杀企图的风险 (aRRR=6.4).
- 与疼痛相关的功能干扰和复发性疼痛显示自杀风险增加.
- 情感和焦虑/压力相关障碍介导了14-16%的疼痛与自杀念头的联系,以及37-48%的疼痛与自杀企图的联系.
结论:
- 频繁疼痛在丹麦11岁的孩子中很常见,并且预测到18岁时,自杀倾向的风险会增加.
- 精神病诊断部分调解了疼痛和自杀倾向之间的关系.
- 自杀预防策略应考虑识别和支持经常经历疼痛的年轻人.
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