美国医疗保健在免疫学中的差异 生物药物获取:系统性审查
Grace C Wright, Ginette A Okoye, Adam C Ehrlich
1AbbVie Inc, Dept GMH1, Bldg ABV1-4SE-113-05, 26525 N Riverwoods Blvd, Mettawa, IL 60045.
The American journal of managed care
|August 19, 2025
概括
美国免疫学患者获得生物药物的差异与保险,种族和成本有关,导致健康状况较差,医疗保健使用增加. 解决这些不平等问题至关重要.
科学领域:
- 免疫学 免疫学 免疫学
- 医疗保健服务研究 医疗服务研究
- 健康差异 在健康上的差异
背景情况:
- 生物药物对免疫病的治疗有了显著的进展.
- 对于许多患者来说,公平地获得这些关键疗法仍然是一个挑战.
- 了解获取差异对于改善患者护理至关重要.
研究的目的:
- 系统地审查美国医疗保健在风湿病学,胃肠病学和皮肤病学中的生物接入方面的差异.
- 检查与有限的生物接入相关的临床和经济结果.
主要方法:
- 2017年至2023年间发表的研究的系统文献综述.
- 在PubMed,Web of Science和Embase数据库中进行了搜索.
- 专注于美国患有免疫病的成年患者 (≥18岁).
主要成果:
- 包括21项研究;生物获取差异被不一致地研究.
- 与差异相关的因素包括保险类型,种族/种族,高自费成本和事先授权.
- 差异与更糟糕的结果相关:增加住院,急诊和治疗延迟,尽管相关性各不相同.
结论:
- 确定了影响美国免疫学生物获取差异的关键因素.
- 这些差异与不良的临床和经济结果有关.
- 突出了潜在的解决方案和进一步研究的需要,以减轻这些不平等现象.
更多相关视频
相关概念视频
Immunodeficiency Diseases
1.2K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
There are three main causes of immunodeficiency...
1.2K
Bioequivalence: Overview
1.2K
Pharmaceutical equivalents, by definition, are drug products with the same active ingredient in the same quantities, encapsulated in identical dosage forms, and intended for the same administration routes. These pharmaceutical equivalents are deemed bioequivalent if the bioavailability of the active entity in the drug preparations is similar. Moreover, pharmaceutical equivalents demonstrating bioequivalence are also regarded as therapeutically equivalent. This means that when used as directed,...
1.2K
Issues And Trends In Healthcare Delivery System
5.8K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.8K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
174
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
174
Factors Influencing Drug Absorption: Disease States and Pharmacology
774
Multiple disease states can significantly influence the oral drug absorption process by affecting blood flow and the functionality of the gastrointestinal (GI) system. Various GI diseases, including conditions that alter GI motility, such as diarrhea, decreased acid secretions (achlorhydria), and infections, have been associated with reduced drug absorption.
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
774
What is the Immune System?
115.9K
Overview
115.9K


