暴露体在精神障碍中的作用:一个范围审查协议
Claudia Gutierrez-Ortiz1,2, Babul Hossain1, Coralie Dessenne3
1Socio-economic, Environmental Health & Health Services (CARES) Research Unit, Department of Precision Health, Luxembourg Institute of Health, 1A-B, rue Thomas Edison, L-1445 Strassen, Luxembourg.
这篇评论探讨了暴露组.
科学领域:
- 环境健康科学 环境健康科学
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 精神障碍的发展是复杂的,在一生中受到多种因素的影响.
- 暴露组概念提供了对终身环境暴露的全面视图.
- 与慢性疾病研究相比,目前的精神障碍研究还没有充分利用暴露组方法.
研究的目的:
- 为了绘制现有的证据,揭示性与精神障碍的关系在整个生命周期.
- 识别和描述在暴露性精神障碍研究中使用的方法.
- 突出这一未充分利用的领域的研究差距.
主要方法:
- 根据PRISMA (系统审查和元分析的首选报告项目) 的指导方针进行范围审查.
- 包括所有年龄组和环境中的观察和干预研究.
- 进行全面的数据库搜索 (MEDLINE,CINAHL,Scopus,Embase,PsycINFO) 并对提取的数据进行叙事和描述分析.
主要成果:
- 该部分在审查完成后将被填写.
- 审查将详细介绍暴露组框架内调查的各种环境因素.
- 将概述当前针对精神疾病的暴露性研究的方法趋势和局限性.
结论:
- 这次范围审查将全面概述暴露基在精神障碍中的作用.
- 结果将为未来的研究方向提供信息,并强调需要在心理健康中更广泛地应用Exposome.
- 这项研究旨在刺激对环境暴露和心理健康的更完整的研究.
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