在患有小脏质量的患者中探索管理偏好:试点研究结果
Clara Diaz1, Maryam Kandi2, Philippe D Violette3
1Research Program in Health Sciences, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, Canada; Division of Urology, Department of Surgery, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Canada.
European urology focus
|August 19, 2025
概括
大多数患有小质 (SRM) 的患者更喜欢不那么侵入性的热切除而不是手术. 患者也倾向于将治疗风险理解为降低死亡率,而不是增加.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 医疗决策的制定 医疗决策的制定
背景情况:
- 小型质 (SRM) 往往是最终治疗的,但积极监测是另一种选择.
- 患者对SRM管理的偏好尚未完全理解.
- 了解患者的偏好对于SRM治疗中共享决策至关重要.
研究的目的:
- 确定患者对管理小质 (SRMs) 的偏好.
- 为了比较患者的偏好,确定治疗方法,如热切除和部分切除术.
- 评估患者愿意接受增加的死亡风险以避免最终治疗.
主要方法:
- 一项多中心前性试点研究,涉及对41名新的SRM患者进行结构化在线访谈.
- 患者审查了结果数据,并表达了热切除除与部分切除的偏好.
- 使用假设情景来确定可接受的死亡风险增加,以拒绝治疗.
主要成果:
- 71%的患者更喜欢热性切除而不是部分切除.
- 5年癌症死亡概率下降治疗的中位数可接受的增加为0.1%.
- 97%的患者更喜欢风险数据作为降低死亡风险.
结论:
- 这项试点研究证实了评估患者对SRM管理偏好的可行性.
- 患者强烈倾向于进行热除,并以降低死亡率的方式呈现风险数据.
- 需要进行更大规模的研究来验证这些发现,并为临床实践提供信息.
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