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长期比较Hydrus与iStent注射微侵入性玻璃眼手术植入物与白内障手术相结合的长期比较结果
Jeremy C K Tan1,2,3, Colin Clement4,5, Paul Healey4
1The University of Sydney Save Sight Institute, Sydney, New South Wales, Australia jeremy.c.tan@unsw.edu.au.
The British journal of ophthalmology
|August 19, 2025
概括
与Hydrus微型支架和iStent注射相结合的法化显示了类似的长期玻璃眼手术成功率. 在48个月内,超过40%的患者在没有额外手术的情况下实现了关键结果.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼的手术 玻璃眼的手术
- 医疗器械技术 医疗器械技术
背景情况:
- 青光眼的管理通常涉及通过药物或手术降低眼内压力 (IOP).
- 微侵袭性玻璃眼手术 (MIGS) 为传统玻璃眼手术提供了不那么侵袭的替代方案.
- 与MIGS植入相结合的法化是一种常见的外科手术方法.
研究的目的:
- 为了比较联合化和Hydrus微型支架 (phaco-Hydrus) 与注射iStent (phaco-iStent) 的长期有效性.
- 在至少48个月的随访中,使用MIGS特定的标准来评估外科成功.
- 在一个大规模的现实世界观察队列中分析结果.
主要方法:
- 对抗玻璃眼盲症注册的回顾性分析.
- 包括接受phaco-Hydrus或phaco-iStent的眼睛,随访时间≥48个月.
- 主要终点: ≥20%的内血压下降和内血压下降≤21mm Hg或≥1药物减少48个月.
- 倾向性得分匹配用于创建可比的子队列进行分析.
主要成果:
- 在48个月后,phaco-Hydrus和phaco-iStent组之间手术成功率没有显著差异 (整体队列:41.2%对43.0%;匹配队列:44.1%对43.2%).
- 在两组中都观察到类似的IOP降低,药物降低和调整后的结果.
- 在两种MIGS器件之间,不良事件的发生率和需要二次手术的情况相似.
结论:
- 在这项大型观察性研究中,法科-Hydrus和法科-iStent在长期外科成功方面表现相似.
- 很大一部分患者 (40%以上) 实现了持续的IOP控制和/或降低药物治疗,而无需进一步进行眼外科手术.
- 这两种MIGS设备都为联合白内障和绿内障手术提供了可行的选择.
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