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Updated: Sep 10, 2025

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孕期早期体重增加和出生体重结果:一个基于中国人口的队列队列
Shuang Zhang1, Lingyan Feng1, Weiqin Li1
1Tianjin Women and Children's Health Center, Tianjin, China.
Pediatric research
|August 19, 2025
概括
孕期早期体重增加显著影响出生体重,影响因母亲的BMI和婴儿的性别而异. 不够的增长可能会导致女性的胎儿生长受限,而过度的增长会增加孕期风险,特别是在女性胎儿.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 围产期流行病学 围产期流行病学
背景情况:
- 孕期早期体重增加 (E-GWG) 对胎儿发育至关重要.
- E-GWG的时间和性别特异性影响尚不清楚,特别是在亚洲人群中.
研究的目的:
- 调查E-GWG与出生体重结果之间的关联.
- 分析E-GWG在不同孕前孕产妇BMI类别的性别特异性影响.
主要方法:
- 这是一项对66291对母婴对进行的回顾性队列研究.
- 使用线性和逻辑回归模型进行分析.
- 检查E-GWG对男性和女性胎儿出生体重的影响.
主要成果:
- E-GWG对出生体重z分数的影响比妊娠后期体重增加更大.
- 在BMI组中,E-GWG与LGA风险正相关,与SGA风险负相关.
- 母亲的BMI和婴儿的性别影响了E-GWG的影响;女性有更高的LGA风险过度E-GWG (超重/肥胖的母亲),而不足的E-GWG对女性 (体重不足的母亲) 构成更高的SGA风险.
结论:
- E-GWG时间和母亲的BMI显著影响出生体重结果和LGA/SGA的风险.
- 性别特定的脆弱性存在:不足的E-GWG风险是女性SGA,而过度的E-GWG风险是LGA,特别是在女性胎儿身上.
- 在亚洲人群中,为了获得最佳的周产期健康,需要量身定制的孕期体重增加指南,考虑到母亲的BMI和婴儿的性别.
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