一个可穿戴的多参数电化学检测和信号处理系统,用于实时汗水分析
Guodong Liu1,2, Heng Wang1, Pingna Zhang3
1School of Mechanical Engineering, Beijing Institute of Technology, 5 South Zhongguancun Street, Haidian District, Beijing, 100081, China.
Mikrochimica acta
|August 19, 2025
概括
这项研究介绍了一种可穿戴系统,用于同时检测汗水生物标志物. 先进的信号处理提高了可穿戴电化学传感器的准确性.
科学领域:
- 生物医学工程 生物医学工程
- 电化学传感器 电化学传感器
- 可穿戴技术可穿戴技术
背景情况:
- 同时监测汗液生物标志物对于非侵入性健康诊断至关重要.
- 现有的可穿戴系统面临信号噪声和准确性方面的挑战.
研究的目的:
- 开发和验证可穿戴的多参数电化学检测系统 (WMEDS),用于实时的汗水分析.
- 实施先进的信号处理技术,以提高数据质量.
主要方法:
- 该WMEDS集成了一个微控制器,双模式信号采集,和蓝牙连接.
- 信号预处理包括Savitzky-Golay过和Z-score差异检测.
- 波形层次值消除用于降低噪声,将信号噪声比提高了12dB.
主要成果:
- 信号处理实现了97.3%的峰值保留率和高于0.99.9的平滑度指数.
- 对于Ca2+和葡萄糖检测,WMEDS显示了与商业电化学工作站相似的结果.
- 对Ca2+ (灵敏度30.6mV/十年) 和葡萄糖 (灵敏度7.7μA/mM) 实现了高精度,定量误差<5.5%.
结论:
- 开发的WMEDS有效地监测出汗生物标志物,具有高准确性和可靠性.
- 先进的信号处理显著提高了可穿戴电化学传感器的性能.
- 该系统符合实际可穿戴汗水监测应用的严格性能要求.
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