Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

38
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
38
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

23
Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
23
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

78
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
78
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

505
The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
505
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

1.8K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.8K
Heart Failure I: Introduction01:27

Heart Failure I: Introduction

54
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
54

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

LncRNA NEAT1 serves as a risk biomarker for acute myocardial infarction complicated by arrhythmia and regulates cardiomyocyte function via miR-624-5p/SAT1.

Archives of biochemistry and biophysics·2026
Same author

Preoperative CT detection of appendiceal neoplasms in suspected acute appendicitis using a simple diameter-and-fecalith criterion: multicenter derivation and validation.

European journal of radiology·2026
Same author

The Effect of Decision Fatigue on Job Stress in Midwives: The Mediating Role of Psychological Capital and the Moderating Effect of Perceived Organizational Support.

Journal of nursing management·2026
Same author

Theoretical Study on the Formation Mechanism of Ti(C,N) Inclusions and Titanium Content Control in High-Grade Non-Oriented Silicon Steel.

Materials (Basel, Switzerland)·2026
Same author

Targeting the NSUN5-circPPAP2A axis reverses immunosuppression and sensitizes renal cell carcinoma to anti-PD-1 therapy.

Cancer letters·2026
Same author

Modelling the Double Layer of Polycrystalline Electrodes: Capacitance, Potential of Zero Charge, and Parsons-Zobel Plot.

ACS electrochemistry·2026

相关实验视频

Updated: Sep 10, 2025

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
06:55

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

14.6K

系统性免疫炎症指数对冠状动脉疾病和心力衰竭患者主要不良心血管事件的影响

ZhiRong Ren1, JinWen Liu2

  • 1Department of Internal Medicine I, Chinese People's Armed Police Force, Shanxi Provincial Corps Hospital, Taiyuan City, 030006, Shanxi Province, China.

European journal of medical research
|August 20, 2025
PubMed
概括
此摘要是机器生成的。

在冠心病和心力衰竭患者中,系统性免疫炎症指数 (SII) 的升高显著增加了重大心血管不良事件 (MACE) 的风险. 高SII水平与这一脆弱群体的生存率较低有关.

关键词:
冠状动脉疾病心脏衰竭主要心血管不良事件倾向性得分匹配系统性免疫炎症指数

更多相关视频

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
14:35

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

Published on: April 17, 2021

8.6K
Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
08:51

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Published on: September 20, 2024

1.5K

相关实验视频

Last Updated: Sep 10, 2025

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
06:55

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

14.6K
Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
14:35

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

Published on: April 17, 2021

8.6K
Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
08:51

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Published on: September 20, 2024

1.5K

科学领域:

  • 心脏病学
  • 免疫学
  • 生物标志物

背景情况:

  • 冠心病 (CHD) 和心力衰竭 (HF) 是重要的心血管负担.
  • 确定可靠的生物标志物来预测心血管不良事件对于患者管理至关重要.

研究的目的:

  • 评估系统性免疫炎症指数 (SII) 对心血管重大不良事件 (MACE) 的预测值.
  • 通过倾向性得分匹配 (PSM) 来确定MACE预测的最佳SII值.

主要方法:

  • 使用倾向分数匹配 (PSM) 来平衡MACE和无MACE患者的基线特征.
  • 接收器操作特征 (ROC) 曲线分析评估了SII的诊断值.
  • 多因素考克斯回归确定了MACE的独立风险因素.
  • 卡普兰- 梅尔曲线根据SII水平对比了无MACE生存率.

主要成果:

  • 在PSM之后,MACE患者的SII,C反应蛋白 (CRP) 和NT-proBNP水平显著提高.
  • 589. 31的SII值显示了MACE的良好诊断性能 (AUC=0. 788).
  • 增加的SII (≥589. 31),CRP和NT-proBNP被确定为MACE的独立风险因素.
  • 患有高SII水平的患者出现MACE的发生率显著高,生存率较低.

结论:

  • 系统性免疫炎症指数 (SII) 是患有心脏病和HF的患者中MACE的一个有价值的预测指标.
  • 在这种患者群体中,SII水平升高与MACE风险增加和生存率降低有关.